Effects of Different Geographical Aspects and Ontogenetic Variability on Total Hypericin Content of Hypericum triquetrifolium Turra. and Hypericum scabrum L.

Determination of Hypericin Content in Callus and Cell Suspension Cultures of Hypericum triquetrifolium Turra

Hypericum triquetrifolium Turra. is a valuable medicinal plant owing to source of many bioactive compounds. Hypericin is one of the significant components among these compounds. The aim of this study was to develope an efficient method allowing to improve hypericin production from calli and cell suspension cultures of Hypericum triquetrifolium Turra. Callus formation was obtained from axenic le...

Pharmacological activities of Hypericum scabrum L.

OBJECTIVES Hypericum spp. (H.) has been used in traditional medicine for their sedative effect for many years. In spite of many works on this genus, little is known about H. scabrum. In this work antidepressant and its protective effect against hypoxia-induced lethality were evaluated. MATERIALS AND METHODS Antidepressant and its protective effects against hypoxia-induced lethality were evalu...

Essential oil composition of Hypericum perforatum L. and Hypericum scabrum L. growing wild in Tajikistan

The essential oils obtained by hydrodistillation from the aerial parts of Hypericum perforatum L. and Hypericum scabrum L. from plants growing wild in Tajikistan were analyzed by GC-MS. Sixty-six compounds were identified in the essential oils of H. perforatum with germacrene D (13.7%), α-pinene (5.1%), (E)-caryophyllene (4.7%), n-dodecanol (4.5%), caryophyllene oxide (4.2%), bicyclogermacrene ...

Effect of time of harvest on hypericin and essential oil content of hypericum performatum L.

Cytotoxic Activity and Apoptosis Induction of Hypericum scabrum L.

BACKGROUND One of the acquired biological hallmarks of tumor multistep development is the resistance of cancer cells to apoptosis; therefore, induction of apoptosis is an important therapeutic approach. Hypericum species are spread throughout the world and have been investigated for their biological properties. OBJECTIVES Our previous studies had demonstrated cytotoxicity of Hypericum scabrum...